PAN Pesticides Database - Chemicals

2,4-dinitrophenol - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water quality standards and physical properties affecting water contamination potential.
Toxicity to aquatic organisms.
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.

Chemical Identification and Use for 2,4-dinitrophenol

Basic Identification Information About This Chemical
Chemical Name: 2,4-dinitrophenol
CAS Number: 51-28-5
U.S. EPA PC Code: 037509
CA DPR Chem Code: 221
Molecular Weight: 184.11
Use Type: Impurity
Chem Class: Dinitrophenol derivative
View Related Chemicals
Additional Resources About This Chemical Class and Use Type
Other Names for this Chemical
About Chemical Synonyms
00221 (CA DPR Chem Code Text ) , 037509 [US EPA PC Code, Text ] , 2,4-dinitrophenol , 221 (CA DPR Chem Code) ) , 24dinitrophenol , 37509 [US EPA PC Code, Numeric ] , 51-28-5 (CAS number) , 51285 , 51285 (CAS number without hyphens) , Dinitrofenol , Dinitrophenol
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products

Signs and Symptoms of 2,4-dinitrophenol Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

2,4-dinitrophenol is a Dinitrophenol compound.

Report a Poisoning

Symptoms of Poisoning with Dinitrophenol Compounds
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- Sweating, thirst, fever, headache, confusion, malaise, and restlessness.
- Hyperthermia, tachycardia, tachypnea in serious cases.
- Characteristic bright yellow staining of skin and hair present with topical exposure.
- Chronic occupational exposure has been shown to lead to cataracts and sometimes glaucoma.

Source for Group Symptoms: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 11.

Treatment for Dinitrophenol Poisoning

See: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 11, page 106.

Symptoms of 2,4-dinitrophenol Exposure from the International Chemical Safety Cards (ICSC)

Report a Poisoning

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Route of Exposure


First Aid

Inhalation (See Ingestion). Fresh air rest (see Notes). Refer for medical attention.
Skin MAY BE ABSORBED! Redness. Roughness. Yellow staining of the skin. (Further see Inhalation). Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
Eyes First rinse with plenty of water for several minutes (remove contact lenses if easily possible) then take to a doctor.
Ingestion Nausea. Vomiting. Palpitations. Collapse. Sweating. Rest. Refer for medical attention.
Notes for ICSC Information
Use all available methods for reducing body temperature. Because of its explosive properties the compound is used in the form of a water paste. UN 0076 applies to the dry compound. CAS 25550-58-7 applies to unspecified isomers of dinitrophenol.

Toxicity Information for 2,4-dinitrophenol

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Carcinogen Cholinesterase
Water Contaminant
Developmental or
Reproductive Toxin
Not Listed
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Detailed Toxicity Information

Acute Toxicity 2
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor
Not Listed
Not Listed
Not Available
No Consensus Value
No NTP Studies

2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
Cancer Information
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Endocrine Disruption
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Reproductive and Developmental Toxicity
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Chemicals of Special Concern
PAN Bad Actors
PAN Dirty Dozen list
Not Listed
Not Listed

Water Pollution Potential and Criteria for 2,4-dinitrophenol

Water Pollution Potential

PAN Ground Water Contaminant Rating Insufficient Data

Water Standards and Criteria

U.S. National Water Quality Criteria
g/L unless noted  
Fresh Water Quality Criteria Continuous Exposure 0  
Fresh Water Quality Criteria Maximum Peak  
Salt Water Quality Criteria Continuous Exposure
Salt Water Quality Criteria Max
Human Consumption of Organisms from Water Source 5,300 Notes: b
Human Consumption of Water and Organisms from Water Source 69.0 Notes: b
Taste and Odor Criteria

Regulatory Information for 2,4-dinitrophenol

International Regulatory Status

UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide
Not Listed
Not Listed
Not Listed

U.S. and California Regulatory Status

U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant

Not Listed
HAPTAC, Industrial chemical

Maximum Tolerance and Residue Levels

Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels
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Ecotoxicity for 2,4-dinitrophenol

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Growth, Physiology
AquaticPlants Physiology
Crustaceans Behavior, Enzyme(s), Mortality
Echinoderms Behavior, Development, Physiology
Fish Accumulation, Behavior, Biochemistry, Enzyme(s), Growth, Histology, Morphology, Mortality, No Effect Coded, Physiology, Population
Insects Mortality
Molluscs Biochemistry, Mortality
Phytoplankton Behavior, Biochemistry, Development, Mortality, Physiology, Population
Zooplankton Accumulation, Avoidance, Behavior, Intoxication, Mortality, Physiology, Population, Reproduction
View All Aquatic Ecotoxicity Studies and References
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Crustaceans Slightly Toxic Slight Toxicity
Fish Moderately Toxic Slight to High Toxicity
Insects Slightly Toxic Slight Toxicity
Molluscs Moderately Toxic Moderate Toxicity
Zooplankton Slightly Toxic Slight to Moderate Toxicity
View All Acute Summaries

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group

Sorry, no honeybee acute toxicity data available for this chemical. Try related chemicals.

Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity
Organism Group Chronic Toxicity  

Related Chemicals for 2,4-dinitrophenol

CAS Number Relation Reason Chemical Name Chem Detail Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
51-28-5 Parent P 2,4-dinitrophenol View View View Impurity No Not Listed
1011-73-0 Related 1 2,4-dinitrophenol, sodium salt View View View Impurity, Breakdown product No Not Listed
32581-06-9 Related 1,6 2,6-dinitrophenol, sodium salt View View View Impurity No Not Listed
25550-58-7 Related 13 Dinitrophenol (mixed isomers) View View View Breakdown product, Impurity No Not Listed
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

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* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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